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2017 | Medical & Veterinary
Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification, which has broad potential for improving diagnosis, prognosis, prediction and risk assessment. This volume offers a unique evaluation of signature differences of childhood, sex-specific and race-specific cancers, broadly illuminating the scope of epigenetic biomarkers in clinical environments. Chapters detail the major epigenetic processes in humans consisting of DNA methylation, histone modifications and microRNAs (miRNAs) involved in the initiation, progression and metastasis of tumors. Also delineated are recent technologies, such as next generation sequencing that are used to identify epigenetic profiles (primarily methylation analysis) in samples (normal, benign and cancerous) and which are highly important to the analysis of epigenetic outcomes.
Sabita Saldanha
(Author)
| Published by | Elsevier Science Publishing Co Inc |
| Edition | Unknown |
| ISBN | 9780128095522 |
| Language | N/A |
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