Measurement and Analysis of Kinetic Isotope Effects

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Measurement and Analysis of Kinetic Isotope Effects

2017 | Medical & Veterinary

Experimental Analysis of Enzyme Mechanism Using Isotope Effects, Volume 596, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. The best, and arguably the only, way to interrogate the transition states of enzyme transition states is kinetic isotope effect analyses. However, technical challenges have limited the application of this powerful approach to a relatively small number of systems. This volume provides the reader who is interested in applying or understanding this research with a survey the major methods currently used for measuring isotope effects on solution and enzyme reactions.



Published by Elsevier Science Publishing Co Inc

Edition Unknown
ISBN 9780128122730
Language N/A

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